翻訳と辞書 Words near each other ・ Interleukin 34 ・ Interleukin 35 ・ Interleukin 36 receptor antagonist ・ Interleukin 37 ・ Interleukin 4 ・ Interleukin 5 ・ Interleukin 5 receptor alpha subunit ・ Interleukin 6 ・ Interleukin 7 ・ Interleukin 8 ・ Interleukin 8 receptor, alpha ・ Interleukin 8 receptor, beta ・ Interleukin 9 ・ Interleukin receptor ・ Interleukin-1 receptor ・ Interleukin-1 receptor family ・ Interleukin-1 receptor-associated kinase ・ Interleukin-1 receptor–associated kinase 4 deficiency ・ Interleukin-10 receptor ・ Interleukin-11 receptor ・ Interleukin-12 receptor ・ Interleukin-13 receptor ・ Interleukin-15 receptor ・ Interleukin-17 receptor ・ Interleukin-18 receptor ・ Interleukin-20 receptor ・ Interleukin-21 receptor ・ Interleukin-22 receptor ・ Interleukin-23 receptor ・ Interleukin-27 receptor Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Interleukin-1 receptor family ： ウィキペディア英語版 Interleukin-1 receptor family Members of the very wide interleukin-1 receptor (IL-1R) family are characterized by extracellular immunoglobulin-like domains and intracellular Toll/Interleukin-1R (TIR) domain. It is a group of structurally homologous proteins, conserved throughout the species as it was identified from plants to mammals. Proteins of this family play important role in host defence, injury and stress. There are four main groups of TIR domain-containing proteins in animals; Toll-like receptors, Interleukin-1 receptor (IL-1R), cytosolic adaptor proteins (such as MyD88 adaptor protein) and insect and nematode Toll. Each of these groups is involved mainly in host defence; Toll receptors are also involved in embryogenesis. == TIR domain == TIR domain is about 200 amino acids long and consists of 3 conserved boxes and between these boxes there are regions of variable length. If due to some mutation all of the three boxes are damaged, there is no surface expression of the protein. If only boxes one and two are mutated, there is loss of signalling activity.〔 There are also highly conserved regions between the three boxes as well. When the receptor is activated TIR domain recruits downstream cytoplasmic signalization adaptor proteins (such as Myd88 adaptor protein). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Interleukin-1 receptor family」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.